Biological Age Test: Epigenetic, Telomere & DNA Tests Compared
Biological age, telomere and DNA tests at Healthi Life in Bangkok cost ฿9,500 to ฿50,000. A biological age test estimates how old your body functions, not how many birthdays you have had, and every result is read with a physician.
Not sure which test answers your question? The Discovery Consultation with Dr. Petch or Dr. First is complimentary.
The 8 terms, in one sentence each
- Biological age
- An estimate of how old your body's cells and systems actually function, which can be older or younger than your birthday age.
- DNA
- The molecule in your cells that carries your genetic instructions: the blueprint your body is built and run from.
- Epigenetics
- The study of chemical marks on your DNA that switch genes on or off without changing the DNA code itself.
- Whole genome sequencing (WGS)
- A test that reads your entire genetic code, all ~3 billion letters of your DNA, instead of a selected set of markers.
- Telomere length
- The length of the protective caps on the ends of your chromosomes, used as one clue to how your cells are aging.
- Telomere in an epigenetic test
- One of several biological clues combined together to estimate how fast your body is aging overall.
- TruAge
- A specific test that estimates your biological age from chemical markers on your DNA.
- TruDiagnostic
- The laboratory company that makes and runs the TruAge test.
What is biological age?
Two people born the same year do not age at the same speed. Biological age puts a number on that difference. It is not a measure of how you feel: it is an estimate built from molecular data, usually DNA methylation, compared with thousands of people whose health was followed over years.
The first widely used epigenetic clock was published by Steve Horvath in 2013 (Genome Biology), from 353 methylation sites across 51 tissue and cell types. Newer clocks no longer predict only your age: DunedinPACE (Belsky et al., eLife, 2022) estimates your pace of aging, in biological years per calendar year. A score of 1.0 means one biological year per calendar year; below 1.0 indicates slower-than-average aging.
DNA vs epigenetics: the code and the switches
Your DNA is the code you were born with. It does not change, so a DNA test is read once: it tells your physician which nutrients, which training and which inherited risks deserve early attention.
Epigenetics is how that code is used. Methylation marks switch genes on and off and respond to sleep, diet, exercise, smoking, alcohol and stress. Because they move, an epigenetic test is a baseline that is re-read, typically at twelve months, to see the direction of travel.
One sentence to remember: DNA answers "what was I born with?"; epigenetics answers "how fast am I aging right now?"
The tests compared — price, sample, turnaround
| Test | What it answers | Sample · results | Price |
|---|---|---|---|
| Telomere Length | How long are the protective caps on my chromosomes? | Blood, PCR · 7–10 days | ฿9,500 |
| BIOAGE biological age test | How old do my cells behave versus my birthday? | Blood or saliva, DNA methylation, U.S. CLIA-certified lab · 14–21 days | ฿15,000 |
| EPISPAN (TruAge COMPLETE) | How fast am I aging, and which of 11 organ systems age fastest? | Blood, 3 mL · 40–45 days | ฿35,000 |
| MyHealthDNA | Which inherited risk factors are worth early attention? | Saliva or blood | ฿16,000 |
| MyLifeStyleDNA | Which diet, training and sleep habits suit my genes? | Saliva or blood | ฿16,000 |
| Premium DNA (whole genome sequencing) | My complete genetic code: 140+ reports across 10 categories | Saliva or cheek swab | ฿22,900 |
| Premium DNA + TruAge COMPLETE | What was I born with, and how fast am I aging now? | DNA 14–21 days · TruAge 40–45 days | ฿50,000 |
Every result is read with a physician. The full menu, with every inclusion, is on the check-up menu; the tests can also be added to a health check-up.
TruAge and TruDiagnostic: what EPISPAN measures
TruDiagnostic is a U.S. laboratory company that develops and runs DNA-methylation tests. TruAge is its biological age test. At Healthi Life, TruAge COMPLETE is offered as EPISPAN: one 3 mL blood draw, analysed by TruDiagnostic, results in 40–45 days, with scores including:
- OMICmAge: your overall biological age against your chronological age.
- SYMPHONYAge: a separate age for 11 organ systems (blood, brain, heart, hormones, immune system, inflammation, kidney, liver, lung, metabolism, musculoskeletal).
- DunedinPACE: your pace of aging, biological years per calendar year.
- Telomere length report, one data point among several.
- Immune age and inflammation score (the inflammation score draws on methylation-based estimates of C-reactive protein and interleukin-6).
- Epigenetic biomarkers, physical fitness estimate, alcohol impact and smoking impact scores.
Your physician sets the baseline, builds the plan around the organ systems aging fastest, then re-reads it at twelve months.
Which test answers your question?
Send us your age, your goal and what you already know about your health. A physician replies with the one test worth doing first — often not the most expensive one.
Telomere length: the standalone test vs the clue inside TruAge
The two are often confused. They measure the same structure in two different ways, for two different purposes.
- Standalone telomere test (฿9,500). The length of the protective caps on your chromosomes is measured directly from blood by PCR, results in 7–10 days. It answers one question: how long are my telomeres compared with people my age?
- Telomere inside an epigenetic test. TruAge reports telomere length as one data point among several, combined into an overall estimate of how fast your body is aging. Telomere length can be estimated from DNA methylation, a method published by Lu et al. (Aging, 2019).
If biological age is your question, the epigenetic test is the broader answer. If telomeres themselves are your question, the standalone test is the direct one.
Whole genome sequencing vs a targeted DNA test
A targeted DNA test reads a selected set of genetic markers, chosen because research links them to a risk or a trait. Whole genome sequencing (WGS) reads everything: all ~3 billion letters of your DNA. Your genome does not change, so it is read once.
At Healthi Life, Premium DNA (฿22,900) is based on whole genome sequencing: saliva or cheek swab, 140+ reports across 10 categories, read with your physician. It is also included in the Longevity Blueprint check-up, with genetic counselling before and after.
Which test should you choose?
- "I want one number to track." BIOAGE, ฿15,000. Re-measure at twelve months.
- "I want to know which organs to work on." EPISPAN (TruAge COMPLETE), ฿35,000: 11 organ ages and pace of aging.
- "I want to know what I was born with." Premium DNA (whole genome sequencing), ฿22,900.
- "I want both." Premium DNA + TruAge COMPLETE, ฿50,000.
- "My question is cellular aging only." Telomere Length, ฿9,500.
What these tests cannot tell you
Epigenetic clocks are validated at population level. For one person, a result is directional and suited to monitoring: it is not a diagnosis, and no test can promise that a result will change. Tell your physician if you have had a blood transfusion or a stem-cell transplant in the past three months; some hormone treatments can also influence interpretation. DNA results describe predispositions, not certainties, and are read with counselling.
Frequently asked questions
What is a biological age test?
A biological age test estimates how old your body functions, as opposed to how many birthdays you have had. Most modern tests read DNA methylation, the chemical marks on your DNA that change with age and lifestyle. At Healthi Life in Bangkok the options are BIOAGE (฿15,000) and EPISPAN, the TruAge COMPLETE test (฿35,000).
How accurate is a biological age test?
Epigenetic clocks such as Horvath's (2013) and DunedinPACE (2022) are validated on large populations. For one person, the result is an estimate: useful as a baseline and to follow a trend when re-measured at twelve months, never a diagnosis.
What is the difference between TruAge and TruDiagnostic?
TruDiagnostic is the US laboratory company that develops and runs the test. TruAge is the name of its biological age test. At Healthi Life, TruAge COMPLETE is offered as EPISPAN: one blood sample, with scores including overall biological age, 11 organ-system ages and pace of aging.
Is a telomere test the same as a biological age test?
No. A standalone telomere test (฿9,500, PCR on blood, results in 7–10 days) measures the length of the protective caps on your chromosomes. Inside an epigenetic test like TruAge, telomere length is reported as one data point among several combined into an overall estimate of how fast you are aging.
What is whole genome sequencing, and does Healthi Life offer it?
Whole genome sequencing (WGS) reads your entire genetic code, all ~3 billion letters of your DNA, instead of a selected set of markers. At Healthi Life, Premium DNA (฿22,900) is based on whole genome sequencing and returns 140+ reports across 10 categories, read with your physician.
Can my biological age go down?
Your DNA code does not change, but epigenetic marks do respond to sleep, diet, exercise and stress. That is why the test is read as a baseline and re-measured at twelve months. No test or clinic can promise a specific change in your result.
References
- Horvath S. DNA methylation age of human tissues and cell types. Genome Biology, 2013;14:R115.
- Belsky DW et al. DunedinPACE, a DNA methylation biomarker of the pace of aging. eLife, 2022;11:e73420.
- Lu AT et al. DNA methylation-based estimator of telomere length. Aging, 2019;11(16):5895–5923.
- National Human Genome Research Institute. Human Genome Project fact sheet. genome.gov.
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