Key Takeaways
- Different mechanisms β Vitalan uses polynucleotides (PN) to support hydration and skin quality; Juvelook uses PDLLA to stimulate collagen.
- Different emphasis β Vitalan for hydration, elasticity, and a fresher surface; Juvelook for firmness and softening fine lines.
- Both are gradual β results build over weeks across a short course and are maintained with periodic sessions.
- Complementary β they are often combined rather than treated as either/or, decided by the physician.
- Pricing β Vitalan ΰΈΏ4,500/session; Juvelook from ΰΈΏ15,000/session. Both individualized after assessment.
- Note β Vitalan (PN) is fish-derived; disclose any fish or salmon allergy. Juvelook is not fish-derived.
This page is for general information and does not constitute medical advice, diagnosis, or treatment. Results vary between individuals. Always consult a qualified physician about your condition. See our full medical disclaimer.
What Skin Boosters Actually Do
"Skin booster" is an umbrella term for injectable treatments that improve the skin from within rather than adding surface product. Different boosters use different active ingredients and therefore act through different biological routes. Two of the most asked-about at our Bangkok house are Vitalan, a polynucleotide (PN) booster, and Juvelook, a PDLLA collagen stimulator. They are frequently compared, but they are not the same category of product.
Vitalan: Polynucleotides (PN) for Hydration and Skin Quality
Vitalan is a polynucleotide booster. Polynucleotides are purified DNA fragments β commonly derived from salmon or trout β used in aesthetic medicine to support the skin's hydration, elasticity, and overall quality. Delivered by fine micro-injection, the aim is a smoother, more supple, better-hydrated surface that builds gradually over the weeks after a session. Because the source is fish DNA, a known fish or salmon allergy is a reason to avoid it, which is one of the checks made before any protocol.
Juvelook: PDLLA for Collagen Stimulation
Juvelook is based on PDLLA (poly-D,L-lactic acid) combined with a hydrogel carrier. Rather than hydrating directly, its primary action is to prompt the skin to build its own collagen over the months following treatment β supporting firmness and softening fine lines. Like other collagen biostimulators, its effect is structural and cumulative rather than an instant change.
Vitalan vs Juvelook: Side-by-Side
| Vitalan (PN) | Juvelook (PDLLA) | |
|---|---|---|
| Active | Polynucleotides (purified fish-DNA fragments) | PDLLA + hydrogel carrier |
| Main emphasis | Hydration, elasticity, skin quality | Collagen stimulation, firmness, fine lines |
| How results appear | Gradual over the weeks after each session | Gradual collagen build over the following months |
| Downtime | Minimal; possible short-lived redness/swelling | Minimal; possible short-lived redness/swelling |
| Allergy note | Fish-derived β disclose fish/salmon allergy | Not fish-derived |
| Price at Healthi Life | ΰΈΏ4,500 / session | From ΰΈΏ15,000 / session |
Which Is Right for You?
If the priority is hydration, a fresher surface, and skin quality, a PN booster like Vitalan is often the starting point. If the priority is firmness and softening fine lines through collagen stimulation, Juvelook may fit better. Many guests are candidates for either, and some are advised a combination β hydration and quality from PN alongside collagen support from PDLLA. There is no single right answer; the suitable option is set by the physician after a skin assessment against your goals and any contraindications.
Safety and Realistic Expectations
Both are medical procedures, delivered by a physician after assessment and informed consent. Neither guarantees a specific outcome, and results vary between individuals. Temporary swelling, redness, or small bruises can occur. Suitability screening covers pregnancy, breastfeeding, active skin infection, autoimmune conditions, and β for the PN booster β fish or salmon allergy. The goal at our house is a natural, built-up improvement, not a sudden change, which is why both are planned as a short course rather than a single visit.
Dr. Napat Hunsajarupan (Dr. First)
Verified PhysicianCo-Founder & Chief Medical Officer
Dermatologist & Peptides Specialist
Dr. Napat Hunsajarupan (Dr. First) is Co-Founder & Chief Medical Officer at Healthi Life, a Dermatologist and Peptides Specialist. He leads Recovery & Performance medicine β IV/NAD+, peptides, cellular therapy and skin regeneration.
