Peptide Therapy

Subcutaneous injection

Every 2–3 days x 15 injections per cycle

Stimulates the pineal gland to regulate melatonin production and may lengthen telomeres — the protective caps on chromosomes that shorten with age.

Sleep and energy improvements over the course of treatment (15 injections).

Those with sleep disorders, age-related decline, immune weakness, or seeking anti-aging benefits.

Not established; consult physician.

Oral capsule

1 capsule daily (500 mg)

Directly raises NAD+ levels — a key molecule for energy production (ATP), DNA repair, and activation of sirtuins (longevity genes). NAD+ declines ~50% by age 50.

Increased energy and metabolic health visible over several weeks of consistent use.

Those seeking anti-aging benefits, better metabolism, physical performance, or cognitive support.

Not established; consult physician.

Subcutaneous injection

Once weekly (10 mg) for 2–3 months, pause for 2 months

A mitochondrial-derived peptide that activates AMPK pathways — helping cells switch to burning fat for energy and mimicking metabolic benefits of aerobic exercise.

Energy and metabolic changes may be noticed within a few weeks.

Individuals seeking weight loss, improved athletic performance, or better metabolic health.

Not established; consult physician.

Subcutaneous injection

Once daily (5–10 mg) for 2–3 months, pause for 2 months

Concentrates in the inner mitochondrial membrane, stabilizing cardiolipin and electron transport chain function — directly repairing damaged cellular power plants and reducing oxidative stress.

Increased energy and reduced signs of aging over weeks of daily use.

Those with mitochondrial dysfunction, heart disease, muscle weakness, or age-related decline.

Not established; consult physician.

Subcutaneous injection

5 days/week (100–200 mcg) — fast 2–3 hours prior to injection

Mimics Growth Hormone Releasing Hormone (GHRH), stimulating the pituitary gland to release natural growth hormone in pulses — extending GH half-life without disrupting natural secretion.

Improved muscle tone, fat loss, and sleep quality over 4–8 weeks.

Those with low growth hormone, seeking anti-aging or fitness benefits, or poor body composition.

Active cancer, tumors, pregnancy. Consult physician.

Subcutaneous injection

5 days/week (100–200 mcg) — fast 2–3 hours prior to injection

A selective ghrelin receptor agonist that gently stimulates GH release without increasing appetite, cortisol, or prolactin — the cleanest GH secretagogue with minimal side effects.

Gradual improvement in body composition and sleep over several weeks.

Individuals with low growth hormone who want fat loss and recovery without side effects.

Cancer, tumors, pregnancy.

Subcutaneous injection

5 days/week (1 mg) — fast 2–3 hours prior to injection

A stabilized GHRH analogue that powerfully stimulates the GH/IGF-1 axis and specifically reduces visceral abdominal fat and triglycerides.

Noticeable visceral fat loss and improved cognition within 3–6 months.

Those with visceral belly fat, low IGF-1, lipodystrophy, or age-related metabolic decline.

Cancer, active tumors, pregnancy.

Oral capsule

100 mg once daily — 1–2 months on, then 1 month off before repeating

A small-molecule direct pan-AMPK activator — the body's master cellular energy sensor. O-304 binds and activates AMPK directly across all tissues simultaneously, shifting cellular metabolism from energy storage to energy utilization. A Phase IIa human trial in T2D patients on Metformin demonstrated significant reductions in fasting plasma glucose, HOMA-IR, blood pressure, and improved microvascular perfusion after 28 days.

Metabolic changes within weeks; significant insulin-sensitivity and body-composition improvements over 1–2 months. Cardiovascular benefits observed at 28 days in clinical trial.

Overweight/obese individuals, metabolic syndrome, insulin resistance, fatty liver (MASLD/NAFLD), type 2 diabetes (adjunct), athletes seeking an oral exercise-mimetic.

Investigational compound — not FDA-approved. Long-term human safety data not yet established. Consult physician. Avoid during pregnancy.

Subcutaneous injection

Once weekly for 2–3 months, pause for 2 months

Activates AMPK pathways in mitochondria, shifting cellular metabolism toward fat oxidation and mimicking the metabolic benefits of exercise.

Metabolic changes and energy improvements within a few weeks.

Individuals seeking weight loss, athletic performance, or metabolic health improvement.

Not established; consult physician.

Oral capsule

One capsule each morning

Inhibits reuptake of serotonin, dopamine, and noradrenaline in the brain — significantly reducing appetite and increasing satiety.

Reduced appetite within days to 1 week; significant weight changes over several months.

Those with obesity, binge eating patterns, or difficulty controlling appetite.

Uncontrolled hypertension, heart disease, MAO inhibitors. Physician supervision required.

Subcutaneous injection

Start 0.5 mg once weekly — titrate monthly based on response

A triple hormone receptor agonist targeting GLP-1, GIP, and Glucagon simultaneously — producing powerful, complementary weight loss effects.

Reduced appetite within days; significant weight loss over 12–48 weeks.

Adults with obesity or type 2 diabetes requiring metabolic optimization.

Personal/family history of medullary thyroid cancer, MEN-2 syndrome, pancreatitis, pregnancy.

Intranasal spray

1 spray in each nostril 1–2 times daily (evening / nighttime)

Regulates the enkephalin system and modulates stress-related neurotransmitters (serotonin, dopamine, BDNF) — reducing anxiety and improving mood while enhancing memory consolidation.

Reduced anxiety and improved sleep within days; cognitive benefits over 1–2 weeks.

Individuals with anxiety, depression, PTSD, ADHD, or stress-related cognitive impairment.

Not established; consult physician.

Intranasal spray

1 spray in each nostril 1–2 times daily (daytime)

Stimulates BDNF (Brain-Derived Neurotrophic Factor), promotes NGF (Nerve Growth Factor), and improves dopaminergic neurotransmission — protecting neurons and enhancing neuroplasticity.

Improved focus and mental energy within days; neuroprotective benefits over weeks.

Those with ADHD, stroke recovery, anxiety, cognitive decline, or neurodegenerative disease.

Not established; consult physician.

Subcutaneous injection

Once daily (0.5–1 mg) for 2 months, pause for 2 months

Upregulates growth hormone receptors, stimulates VEGF (angiogenesis), and activates the FAK-paxillin pathway — accelerating healing across tendons, muscles, gut, and brain.

Pain reduction and measurable healing within 1–2 weeks of daily use.

Those with gut issues (leaky gut, IBS, GERD) or musculoskeletal injuries.

Avoid during active cancer treatment; not established otherwise.

Subcutaneous injection

Once daily (0.5 mg) for 2 months, pause for 2 months

Stimulates angiogenesis (new blood vessel growth) and activates satellite cells for muscle regeneration — broadly promoting tissue repair throughout the body.

Faster healing of acute injuries within weeks; chronic injury response over 1–2 months.

Athletes, post-surgery patients, or those with acute or chronic musculoskeletal injuries.

Not established; consult physician.

Oral capsule

1–2 capsules daily (500–1,000 mcg)

Locally repairs the intestinal mucosa, reduces inflammatory cytokines, and restores gut barrier integrity — specifically beneficial for gastrointestinal conditions.

GI symptom improvement within 1–2 weeks; full gut restoration over 1–2 months.

Those with IBD, IBS, leaky gut, ulcerative colitis, or GERD.

Avoid during cancer treatment; not established otherwise.

Subcutaneous injection

Once daily (2 mg) for 2–3 months, pause for 2 months

A naturally occurring copper peptide that stimulates collagen, elastin, and glycosaminoglycan synthesis; attracts immune cells and fibroblasts to wound sites; and activates antioxidant enzymes for tissue repair.

Improved wound healing and skin quality over 2–4 weeks; hair effects over 1–3 months.

Those with skin damage, scars, hair loss, or seeking anti-aging skin and tissue effects.

Not established; consult physician.

Oral capsule

One capsule once daily with or without food

A tripeptide derived from alpha-MSH that suppresses NF-kB signaling and reduces pro-inflammatory cytokines (IL-6, TNF-alpha) — without stimulating melanin production or skin darkening.

Reduced inflammation over days to weeks; gut symptom improvement over 1–2 months.

Those with inflammatory bowel disease, Crohn's, skin disorders, or slow wound healing.

Not established; consult physician.

Subcutaneous injection

Every 2–3 days x 15 injections per cycle

Regulates the pineal gland's melatonin secretion — restoring natural circadian rhythm and sleep architecture — while stimulating telomerase activity to protect telomere length.

Sleep and energy improvements progressively over the 15-injection treatment course.

Those with sleep disorders, age-related sleep degradation, or seeking anti-aging benefits.

Not established; consult physician.

Subcutaneous injection

2–6 hours before bedtime (250–500 mcg)

Modulates delta-wave (slow-wave) sleep initiation, reduces nocturnal ACTH and cortisol, and exerts a stress-protective effect on the hypothalamic-pituitary axis.

Improved sleep quality within days; most notable for stress-related insomnia.

Individuals with insomnia, stress-related sleep issues, chronic pain, or shift workers.

Not established; consult physician.

Subcutaneous injection

As needed, up to 3 times/week — 1–2 hours prior to desired effect (1–2 mg/injection)

Acts on MC4R melanocortin receptors in the hypothalamus — directly activating the brain's sexual arousal pathways. Effective for both men and women regardless of hormonal status.

Arousal enhancement within minutes to 1–2 hours of administration.

Men with erectile dysfunction or women with hypoactive sexual desire disorder.

Uncontrolled hypertension, pregnancy, breastfeeding.

Intranasal spray

1 spray in each nostril once daily

Same MC4R melanocortin receptor activation as injectable PT-141 — delivered nasally for faster absorption and convenience without injection.

Arousal effects within minutes to 1 hour.

Those preferring non-injection delivery for libido and sexual function support.

Uncontrolled hypertension, pregnancy.

Intranasal spray

1 spray in each nostril once daily

The endogenous 'bonding hormone' — binds oxytocin receptors in the limbic system, reducing social anxiety, increasing trust and empathy, and enhancing physical intimacy.

Subtle mood, bonding, and social effects within minutes; cumulative with regular use.

Those with low libido, difficulty with intimacy, social anxiety, or relationship challenges.

Not established; consult physician.

Subcutaneous injection

Once daily (100–200 mcg) for 2–3 months

Activates GnRH neurons in the hypothalamus, triggering pulsatile release of LH and FSH — the master hormones that drive natural testosterone production in men and ovarian hormone production in women.

Hormonal changes within days to weeks; fertility and libido improvements over 1–3 months.

Those with low LH/FSH-driven hypogonadism, infertility, or low libido from hormonal insufficiency.

Hormone-sensitive cancer, pregnancy (physician monitoring required).

Subcutaneous injection

500–1,000 mcg SC once daily (loading weeks 1–4, maintenance weeks 5–8)

A 15-amino acid peptide derived from gastric juice. Upregulates growth hormone receptors in tendon fibroblasts, modulates the nitric oxide system, and activates the FAK-paxillin signalling pathway — accelerating structural repair of connective tissue, muscle, and gut lining.

Subcutaneous injection

500–1,000 mcg SC once daily (loading weeks 1–4, maintenance weeks 5–8)

A synthetic version of Thymosin Beta-4, found in highest concentrations at injury sites. Sequesters G-actin monomers, promoting cellular migration and actin polymerization — the body's primary signal to begin wound healing and angiogenesis.

Includes: private physician consultation, personalised dose prescribed per assessment, certified partner pharmacy sourcing, 8-week protocol with mid-point review, SC injection training, and 90-day follow-up reassessment. Ideal for acute injuries (muscle tears, tendon ruptures, ligament sprains, post-surgical recovery, rotator cuff, ACL/PCL, Achilles repair) and chronic/degenerative presentations (tendinopathy, chronic back pain, repetitive strain, non-healing wounds, nerve damage, inflammatory bowel conditions, exercise-induced gut permeability).

Physician-supervised use only. BPC-157 and TB-500 are research peptides, not FDA-approved for any specific indication. Patients with active malignancy should consult their oncologist before initiating.